David Koelle, MD

Professor, Division of Allergy and Infectious Diseases, Department of Medicine

Joint Professor, Department of Laboratory Medicine & Pathology

University of Washington

Affiliate Investigator, Fred Hutch Cancer Center and Benaroya Research Institute

Objectives:

1. Review basic principles of T cell receptor biology, specimen types and sequencing platforms available
2. Understand uses and limitations of T cell receptor sequencing in vaccine research
3. Understand uses and limitations of T cell receptor sequencing for clinical diagnostics

Speaker disclosures: Dr. David Koelle discloses a financial relationship with Curevo, Inc. (Member, Scientific Advisory Board), MaxHealth LLC (Member, Scientific Advisory Board), & Sanofi Pasteur (Research Support) within the past 24 months. All conflicts of interest have been mitigated.

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Grant Acknowledgment: None

Planning Committee Disclosures:

The following members have not had any financial relationships with any ineligible entities in the past 24 months: Lindsey Durowoju, MD;  Ashley Eckel, MD, PhD; Susan Fink, MD, PhD; Noah Hoffman, MD, PhD; Nabiha Huq Saifee, MD, PhD; Andrew Laitman, MD, PhD; and Cate Paschal, PhD.

The following members disclose financial relations with ineligible entities within the past 24 months: Sean Murphy, MD, PhD Sound Vaccines Inc. (Co-founder/equity); Daniel Sabath, MD RareCyte, Inc (Research support); Brian Shirts, MD PhD Sana Biotechnology, Inc. (consulting);  Hamilton Tsang, MD Pfizer, Roche, Johnson and Johnson, CRISPR therapeutics (stock holder).

All relevant financial relationships listed have been mitigated.

Sponsored by the University of Washington School of Medicine, the Department of Laboratory Medicine, and the Office of Continuing Medical Education. Sign-in is required to receive Continuing Medical Education (CME) or Continuing Education (CE) credit.

The University of Washington School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The University of Washington School of Medicine designates this live activity for a maximum of 30 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. (Each session is 1.0 credit.)