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MolES/Nano Seminar: Ravi Bellamkonda, Georgia Institute of Technology Biomedical Engineering and Emory School of Medicine
WhenTuesday, Jan. 7, 2014, 2:30 – 3:30 p.m.
Description

Speaker's Website
Host: Assoc. Prof. Suzie Pun, Bioengineering

Engineering cell migration for nerve repair and brain tumor therapy

Control of cell migration is important for healing of damaged tissues and on the flip side, cell invasion is at the root of the challenge that clinicians face in treating brain tumors.  In my laboratory we have been exploring the use of thin film mediated topographical cues to enable efficient and controlled migration of cells.  In the peripheral nerve context, induction of Schwann cell migration into critically sized nerve gaps enables bridging of long nerve gaps. 

In the context of brain tumors, we are designing novel devices to control the invasion of brain tumors along paths that we specify using topographical guidance of brain tumors in vivo. We demonstrate, for the first time to our knowledge, that topographical cues presented by thin films enable moving a primary tumor from an intracortical region to an extracortical hydrogel sink where the tumor cells are killed.  This novel approach of bring the tumor to the drug rather than the drug to the tumor is enabled by our ability to design constructs that enable controlled, directional migration of invasive brain tumors.

Campus locationJohnson Hall (JHN)
Campus room175
Event typesLectures/Seminars
Event sponsorsThe weekly seminar series organized by Molecular Engineering and Sciences Institute provides a forum for bringing national and international leaders in nanoscale science and technology to campus, and for graduate students enrolled in our Dual Ph.D. program in Nanotechnology to present their research. The campus and public are welcome to attend.
Linkdepts.washington.edu…
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