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Science in Medicine - “Ensuring an Equal Genetic Inheritance: A Tale of Yeast, Lasers, and the Effort to Rebuild one of Nature’s most Complex Molecular Machines.”
WhenThursday, Nov 15, 2018, 1 – 2 p.m.
Campus locationWilliam H. Foege Genome Sciences (GNOM)
Campus roomFoege Auditorium
Event typesLectures/Seminars
Event sponsorsThe Office of Research and Graduate Education 
School of Medicine 
Description

Dr. Davis investigates the cellular machinery responsible for genome partitioning during cell division. The
kinetochore is a highly conserved element of this machinery; it is the vital link between chromosomes and
the microtubules that pull replicated chromosomes apart. Davis and her colleagues use diverse molecular
techniques–– from single-molecule biophysical approaches to biochemistry, genetics, and microscopy––
to investigate the dynamic assembly, structure, and regulation of the kinetochore. Their work reveals a
sequential and coordinated pattern of protein-protein interactions that contribute to the mechanics of cell
division and the fidelity of genome inheritance

Linkwww.uwmedicine.org…
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